의료진 소개
| 성명 | 이은직 교수 |
|---|---|
| 진료과 | 세브란스병원-내분비내과, 뇌하수체종양센터, 갑상선질환 클리닉 |
| 전문진료분야 | (1) 뇌하수체 전문 크리닉 (종양, 말단비대증, 프로락틴종양, 쿠싱병, 뇌하수체기능저하, 성장호르몬결핍) (2) 갑상선 질환크리닉 (항진증, 저하증, 갑상선 안구병증) |
진료 시간표
| 진료시간 | 월 | 화 | 수 | 목 | 금 | 토 | ||
|---|---|---|---|---|---|---|---|---|
| 오전 | 뇌하수체종양 센터 |
갑상선 크리닉 | 뇌하수체종양 센터 |
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| 오후 | ||||||||
갑상선, 내분비질환, 뇌하수체 크리닉
기본정보
논문저서
| 교육 및 임상 경력 |
1984 - 1988 세브란스병원 수련의 (내과)
1991 – 1997 연세의대 내분비내과 강사, 조교수
1995 -2006 미국 노스웨스턴 의대 내분비내과 선임연구원,조교수, 부교수
1995 -1999 미국 노스웨스턴 의과대학 내분비내과 선임연구원
2006- 현재 미국 노스웨스턴 의대 내분비내과 겸임교수
연세의대 내분비내과 교수 |
|---|---|
| 학술관련경력 |
대한내분비학회 연구, 학술, 윤리, 기획 이사, 부회장
|
| 주요 관심분야 |
뇌하수체질환 (말단비대증, 프로락틴선종, 쿠싱병, 뇌하수체염, 요붕증, 사춘기 2차 성징장애)
갑상선질환 (항진증, 저하증, 안구병증)
|
| 학력사항 |
1984 연세대학교 의과대학 학사
1988 연세대학교 의과대학 석사
1994 연세대학교 의과대학 박사
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1. Lee EJ, Jameson JL: Gonadotropin (FSH and LH) pituitary tumors. Differential diagnosis and treatment. In Wierman ME, ed. Diseases of the pituitary. Diagnosis and treatment. Humana Press; Totowa, 1997, pp. 247-272. 2. Lee EJ, Jameson JL: Gene therapy vector for pituitary tumor. Molecular Endocrinology: Method and protocol Humana Press; Totowa, 2004 (in press) Peer Reviewed Journal (from 1993) 1. Lee EJ, Lee BS, Lee HC, et al: Growth hormone response to L-dopa and pyridostigmine in women with polycystic ovarian syndorme. Fertil Steril 60:53-57, 1993 2. Lee HC, Lee KW, Chung CH, Chung YS, Lee EJ, Lim SK, Kim KR, Huh KB, Lee SC, Kwon OW: IGF-1 of serum and vitreous fluid in patients with diabetic proliferative retinopathy. Diabetes Res Clin Pract. 24:85-88, 1994 3. Lee EJ, Kim KR, Lee KM, Lim SK, Lee HC, Lee JH, Lee DJ, Huh KB: Reduced growth hormone response to L-dopa and pyridostigmine in obesity. International J of Obesity 18:465-468, 1994 4. Lee EJ, Kim KR, Lim SK, Lee HC, Kim DI, Kim SH, Huh KB: Reduction in size of a thyrotropin secreting pituitary adenoma treated with octreotide acetate (somatostatin analog). European J of Endocrinology 131:109-112, 1994 5. Lee EJ, Nam SY, Kim KR, et al: Acipimox potentiates GH response to GHRH with or without pyridostigmine by lowering serum free fatty acid in normal and obese subjects. J of Clin Endocrinol Metab 80:2495-2498, 1995 6. Lee EJ, Kim KR, Lee HC, et al: Acipimox potentiates GH response to GHRH by decreasing serum free fatty acid levels in hyperthyroidism. Metabolism 44:1509-1512, 1995 7. Lim SK, Park YS, Park JM, Song YD, Lee EJ, Kim KR, Lee HC, Huh KB: lack of association between vitamin D receptor genotypes and osteoporosis in Koreans. J Clin Endocrinol Metab. 80:3677-81, 1995 8. Nam SY, Lee EJ, Kim KR, et al: Long term treatment of acipimox potentiates GH response to GHRH by lowering serum free fatty acid in obese subjects. Metabolism 45:594-597 1996 9. Lee HC, Ikegami H, Fusisawa T, Ogihara T, Park SW, Chung YS, Lee EJ, Lim SK, Huh KB, Kim KR, Kim YS, Lee DS, Kim DH: Role of HLA class II alleles in Korean patients with IDDM. Diabetes Res Clin Pract. 31:9-15, 1996 10. Lee HC, Nam MS, Nam SY, Cha BS, Lee JH, Song YD, Lee EJ, Lim SK, Kim KR, Kim YS, Park K, Huh KB: Posttransplant diabetes mellitus after renal transplantation in Korea. Transplant Proc. 28:1159-60, 1996 11. Nam SY, Lee EJ, Kim KR, Cah BS, Song YD, Lim SK, Lee HC, Huh JB: Effect of obesity on total and free insulin-like growth factor (IGF)-1, and their relationship to IGF-binding protein (BP)-1, IGFBP-2, IGFBP-3, insulin, and growth hormone. Int J Obes Relat Metab Disord. 21:355-9, 1997 12. Kim JH, Lee EJ, Kwon OH: Apolipoprotein E genotyping and phenotyping in type II diabetes mellitus patients with hypertriglyceridemia. Clin Biochem 30: 47-52, 1997 13. Lim SK, Won YJ, Lee JH, Kwon SH, Lee EJ, Kim KR, Lee HC, Huh KP, Chung BC: Altered hydroxylation of estrogen in patients with postmenopausal osteopenia. J Clin Endocrinol Metab 82:1001-1006, 1997 14. Lee HC, Song YD, Li HR, Park JO, Suh HC, Lee EJ, Lim SK, Kim KR, Huh KB: Mitochondrial gene transfer ribonucleic acid (tRNA) Leu (UUR)3243 and tRNA (Lys) 8344 mutations and diabetes mellitus in Korea. J Clin Endocrinol Metab 82:372-374, 1997 15. Layman LC, Lee EJ, Peak DB, et el: Delayed puberty and hypogonadism caused by a compound heterozygous mutation in the follicle stimulating hormone beta-subunit gene. New Engl J Med 337:607-611, 1997 16. Lee EJ, Anderson LM, Thimmapaya B, Jameson JL: Targeted expression of toxic genes directed by pituitary hormone promoters: A potential strategy for adenovirus-mediated gene therapy of pituitary tumors. J Clin Endocrinol Metab 84:786-794,1999 Lu M, Kwan T, Yu C, Chen F, Freedman B, Schafer JM, Lee EJ, Jameson JL, Jordan C, Cryns VL: PPAR agonists promote TRAIL-induced apoptosis by reducing surviving levels via cyclin D3 repression and cell cycle arrest. J Biol Chem 2005 Feb 25;280(8):6742-51 Park Y, Maizels E, Feiger Z, Alam H, Peters C, Woodruff T, Lee EJ, Jameson JL, Hunzicker-Dun M: Induction of cyclin D2 in rat granulosa cells requires FSH-dependent relief from FOXO1 repression coupled with positive signals from Smad Dec 21 2004 J Biol Chem 2005 Mar 11;280(10):9135-48 Lee EJ, Russell T, Hurley L, Jameson JL. Pit-1 induces transient differentiation of adult hepatic stem cells into lactotrope lineage in vivo. Mol Endocrinology 2005 April 19(4): 964-971 Freedman B, Lee EJ, Park Y, Jameson JL: A Dominant Negative PPARγ Knock-in Mouse Exhibits Lipodystrophy and Insulin Resistance J Biol Chem 2005 Apr 29;280(17):17118-25 Lee EJ, Jameson JL: Gene therapy of pituitary diseases (Invited Review). J of Endocrinol 2005 Jun 185: 353-362. Burdette JE, Jeruss JS, Kurley SJ, Lee EJ, Woodruff TK: Activin A mediates growth inhibition and cell cycle arrest through Smads in human breast cancer cells. Cancer Research 2005 Sep 65:7968-7975 Kim DM, Ahn CW, Kim KR, Hong SW, Nam MS, Cha BS, Lim SK, Lee HC, Lee EJ: Duodenal Somatostatinoma Presenting with Diabetic Ketoacidosis. J Clin Endocrinol Metab 90(11):6310-5 Glidewell-Kenney C, Weiss J, Lee EJ, Pillai S, Ishikawa T, Arizi E, Jameson JL: ERE-independent ERalpha target genes differentially expressed in human breast tumors Mol Cell Endocrinol. 2005 245:53-59 Chin-Chance CVT, Newman MV, Kruger J, Lee EJ, Lowe Jr WL: Activation of c-jun NH2-terminal kinase contributes to cytokine-mediated inhibition of insulin gene transcription. J Invest Med 2006 54(3) : 132-142 Lim HJ, Lee S, Lee KS, Park JH, Jang Y, Lee EJ, Park HY: PPARγ activation induces CD36 expression and stimulates foam cell like changes in rVSMCs. Prostaglandins and Other Lipid Mediators 80: 165-174 IF:3.5 2006 O’Brien JE, Peterson T, Tong MH, Lee EJ, Pfaff L, Hewitt SC, Korach KS, Weiss J, Jameson JL: Estrogen induced proliferation of uterine epithelial cells is independent of estrogen receptor binding to classical estrogen response elements. J Biol Chem . 2006 281(36): 26683-26692 Browne M, Stellmach V, Cornwell M, Chung C, Dol JA, Lee EJ, Jameson JL, Reynolds M, Superina RA, Abramson LP, Crawford SE. Gene Transfer of Pigment Epithelium-Derived Factor Suppresses Tumor Growth and Angiogenesis in a Hepatoblastoma Xenograft Model. Pediatr Res 2006 60(3): 282-287 Cho MA. Jeong SJ, Eom SM, Park HY, Lee YJ, Park SE, Park SY, Rhee Y, Kang ES, Ahn CW, Cha BS, Lee EJ, Kim KR, Lee HC, Lim SK: The H723R mutation in the PDS/SLC26A4 gene is associated with typical Pendred Syndrome in Korean patients. Endocrine 2006 Oct; 30 (2): 237-43 Song YD*, Lee EJ* (co-first author), Yashar P, Pfaff LE, Kim SY, Jameson JL: Islet cell differentiation in liver by combinatorial expression of transcription factors neurogenin-3, BETA2, and RIPE3b1. Biochem Biophys Res Commun. 2007 Mar 9;354(2):334-9. Park SE, Cho MA, Kim SH, Rhee Y, Kang ES, Ahn CW, Cha BS, Lee EJ, Kim KR, Lee HC, Lim SK. : The adaptation and relationship of FGF-23 to changes in mineral metabolism in Graves' disease. Clin Endocrinol (Oxf). 2007 Jun;66(6):854-8. Epub 2007 Apr 15. Park SJ, Kim SJ, Rhee Y, Byun JH, Kim SH, Kim MH, Lee EJ, Lim SK. Fidgetin-like 1 gene inhibited by basic fibroblast growth factor regulates the proliferation and differentiation of osteoblasts. J Bone Miner Res. 2007 Jun;22(6):889-96. Han SJ, Kim TS, Jeon SW, Jeong SJ, Yun M, Rhee Y, Kang ES, Cha BS, Lee EJ, Lee HC, Lim SK.: Analysis of adrenal masses by 18F-FDG positron emission tomography scanning. Int J Clin Pract. 2007 May;61(5):802-9. Epub 2007 Mar 2. Cho MA, Lee MK , Nam KH, Chung WY, Park CS, Yang WI, Rhee Y, Lim SK, Lee HC, Lee EJ*: Expression and role of estrogen receptor and in medullary thyroid carcinoma: Different role in cancer growth and apoptosis. J Endocrinol 2007 Nov;195(2):255-63. Lee Y, Kwon MK, Kang ES, Park YM, Choi SH, Ahn CW, Kim KS, Park CW, Cha BS, Kim SW, Sung JK, Lee EJ, Lee HC.: Adenoviral vector-mediated glucagon-like peptide 1 gene therapy improves glucose homeostasis in Zucker diabetic fatty rats. J Gene Med. 2008 Mar;10(3):260-8 Cho MA, Yashar P, Kim SK, Noh TW, Gillam MP, Lee EJ (Correspondence), Jameson JL. HoxD10 gene delivery using adenovirus/adeno-associate hybrid virus inhibits the proliferation and tumorigenicity of GH4 pituitary lactotrope tumor cells. Biochem Biophys Res Commun 2008 Jul 4;371(3):371-4. Epub 2008 Apr 28. Park SY, Lee EJ, Emge D, Jahn CL, Jameson JL. A Phenotypic Spectrum of Sexual Development in Dax1(Nr0b1)-Deficient Mice: Consequence of the C57BL/6J Strain on Sex Determination. Biol Reprod. 2008 Jul 16. Lee EJ, Kim JM, Lee MK, Jameson JL: Splice Variants of the Forkhead box protein AFX Exhibit Dominant Negative Activity and Inhibit AFX-mediated Tumor Cell Apoptosis. PLoS ONE 2008 Jul 23:3(7):e2743 Choi H, Kim S, Moon JH, Lee YH, Rhee Y, Kang ES, Ahn CW, Cha BS, Lee EJ, Kim KR, Lee HC, Jeong SY, Kim HJ, Lim SK. Multiple endocrine neoplasia type 1 with multiple leiomyomas linked to a novel mutation in the MEN1 gene. Yonsei Med J. 2008 Aug 30;49(4):655-61 Kim SH, Kim YM, Cho MA, Rhee Y, Hur KY, Kang ES, Cha BS, Lee EJ, Lee HC, Lim SK. Echogenic Carotid Artery Plaques are Associated with Vertebral Fractures in Postmenopausal Women with Low Bone Mass. Calcif Tissue Int. 2008 May 22. [Epub ahead of print] Choi HS, Kim SH, Rhee Y, Cho MA, Lee EJ, Lim SK. :Serum parathyroid hormone is associated with carotid intima-media thickness in postmenopausal women. Int J Clin Pract. 2008 Sep;62(9):1352-7. Epub 2008 Jul 24. Lee YH, Kim JM, Lee EJ*: Functional expression of CXCR4 in somatotrophs: SDF1 activates growth hormone (GH) gene, GH production and secretion, and cellular proliferation. J Endocrinol 2008 Aug 27. [Epub ahead of print] Lee EJ*, Ahn JY, Noh TW, Cho MA, Kim SH, Kim TS, Kim SH: Tumor tissue identification in the pseudocapsule of pituitary adenoma: Should the pseudocapsule be removed for total resection of pituitary adenoma? Neurosurgery 2009 (in press) Alam H, Maizels E, Park Y, Lee EJ, Jameson JL, Ashcroft M, Hunzicker-Dunn M: VEGF induction by FSH-stimulated hypoxia-inducible factor-1 activation in ovarian granulose cells requires the extracellular-regulated kinase pathway. Endocrinology (in press) Stereotactic injection of adenoviral vector that targets pituitary specific cell type: Implication for gene therapy NEUROSURGERY 46 0:1461~1469,2000 Absence of activating mutation of GHRH receptor in acromegalic tumor J Clin Endocrinol Metab 86 0:3989~3995,2001 Adenovirus directed expression of dominant negative estrogen receptor induces apoptosis in breast cancer cells and regression of tumors in nude mice MOLECULAR MEDICINE 7 11:773~782,2001 Adenovirus-mediated targeted expression of toxic genes to ACTH-producing pituitary tumors using POMC promoter J Clin Endocrinol Metab 86 0:3400~3409,2001 Dominant negative estrogen receptor induces apoptosis in pituitary lactotrope adenoma cells and inhibits tumor growth in nude mice ENDOCRINOLOGY 142 0:3756~3763,2001 Inherited disorders of the gonadotropin hormones Mol Cell Endo 179 0:89~96,2001 Restoration of GHRH responsiveness of pituitary GH3 cells by adenovirus-directed expression of the human GHRH receptor ENDOCRINOLOGY 142 0:414~420,2001 Activation of phosphatidylinositol 3-kinase contributes to insulin-like growth factor-1 mediated inhibition of pancreatic beta cell death. ENDOCRINOLOGY 143 0:3802~3812,2002 An estrogen receptor (ER) alpha DNA-binding domain knock-in mutation provides evidence for nonclassical ER pathway signaling in vivo MOLECULAR ENDOCRINOLOGY 16 10:2188~2201,2002 Cell specific Cre-mediated activation of the diphtheria toxin gene in pituitary tumor: Potential for cytotoxic gene therapy HUMAN GENE THERAPY 13 0:0~0,2002 Expression of a Tissue-Specific Calpain Induced by Estrogen in the Pituitary: Evidence of Presence of an Estrogen Response Element in the 5’-Flankin BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 295 0:261~266,2002 Inhibitory effects of antagonistic analogs of growth hormone releasing hormone (GHRH) on GH3 pituitary cells expressing the human GHRH receptor The Journal of endocrinology 175 2:425~434,2002 A dominant negative PPAR; mutant shows altered cofactor recruitment and inhibits adipogenesis of 3T3-L1 cell DIABETOLOGIA 46 0:365~377,2003 Duodenal somatostatinoma associated with diabetic ketoacidosis presumably caused by somatostatin-28 hypersecretion JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 90:6310~6315,2005 Estrogen-induced proliferation of uterine epithelial cells is independent of estrogen receptor α binding to classical estrogen response elements JOURNAL OF BIOLOGICAL CHEMISTRY 281 36:26683~26692,2006 제2형 당뇨병환자에서 인슐린양 성장인자 결합단백질-3(iIGFBP-3)promoter-202 A/C 유전자 다형성 임상당뇨병학회지(Clinical Diabetes) 7 2:169~180,2006 Role of the Mitogen-Activated Protein Kinases in Cytokine-Mediated Inhibition of Insulin Gene Expression JOURNAL OF INVESTIGATIVE MEDICINE 54 3:132~142,2006 Gene Transfer of Pigment Epithelium-Derived Factor Suppresses Tumor Growth and Angiogenesis in a HepatoblastomaXenograft Model PEDIATRIC RESEARCH 60 3:282~287,2006 말기신부전환자에서 인슐린항체에 의한 자가면역성 저혈당증 1예 대한내분비학회지(Joornal of the Korean Society of Endocrinol) 21 6:536~541,2006 The H723R mutation in the PDS/SLC26A4 gene is associated with typical Pendred syndrome in Korean patients ENDOCRINE 30 2:237~243,2006 골감소를 보이는 가족성 저칼슘뇨성 고칼슘혈증 1예 대한내분비학회지(Joornal of the Korean Society of Endocrinol) 21 6:583~588,2006 PPARγ activation induces CD36 expression and stimulates foam cell like changes in rVSMCs PROSTAGLANDINS & OTHER LIPID MEDIATORS 80 3-4:165~174,2006 Analysis of adrenal masses by 18F-FDG positron emission tomography scanning INTERNATIONAL JOURNAL OF CLINICAL PRACTICE 61 5:802~809,2007 The adaptation and relationship of FGF-23 to changes in mineral metabolism in Graves` disease CLINICAL ENDOCRINOLOGY 66 6:854~858,2007 The clinical and immunogenetic characteristics of adult-onset type 1 diabetes mellitus in Korea ACTA DIABETOLOGICA 44 3:45~54,2007 당뇨병 신증을 동반한 환자에서 단핵구 내 NF-кB 및 AP - 1의 활성화 당뇨병학회지(J Korean Diabetes Assoc) 31 3:261~273,2007 당뇨병 미세혈관 합병증에서 생체 각막 공초점 현미경(In vivo Corneal Confocal Microscopy)과 신경성장인자(Nerve GrowthFactor)의 의의 당뇨병학회지(J Korean Diabetes Assoc) 31 4:351~361,2007 일시적인 뇌하수체기능저하증을 동반한 터너 증후근 1예 대한내분비학회지(Journal of the Korean Society of Endocrinology) 22 4:266~271,2007 Islet cell differentiation in liver by combinatorial expression of transcription factors Neurogenin-3, BETA2, and RIPE3b1 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 354:334~339,2007 Fidgetin-like 1 gene inhibited by basic fibroblast growth factor regulates the proliferation and differentiation of osteoblasts. JOURNAL OF BONE AND MINERAL RESEARCH 22 6:889~896,2007 Expression and role of estrogen receptor α and β in medullary thyroid carcinoma: Different roles in cancer growth and apoptosis JOURNAL OF ENDOCRINOLOGY 195:255~263,2007 Expression and regulation of osteoprotegerin in adipose tissue YONSEI MEDICAL JOURNAL 48 5:765~772,2007 제2형 당뇨병 환자에서 인슐린저항성 지표와 프레밍험 위험도와의 관련성 한국역학회지(Korean Journal Of Epidemiology) 29 1:34~46,2007 Internet Diabetic Patient Management Using a Short Messaging Service Automatically Produced by a Knowledge Matrix System DIABETES CARE 30 11:2857~,2007 Internet diabetic patient management using a short messaging service automatically produced by a knowledge matrix system DIABETES CARE 30 11:2857~2858,2007 The clinical and immunogenetic characteristics of adult-onset type 1 diabetes mellitus in Korea ACTA DIABETOLOGICA 44 2:45~54,2007 Cerebral arterial pulsatility and insulin resistance in type 2 diabetic patients Diabetes Research And Clinical Practice 79:237~242,2008 Visceral fat thickness predicts fatty liver in Koreans with type 2 diabetes mellitus Journal Of Korean Medical Science 23:256~261,2008 Adenoviral vector-mediated glucagon-like peptide 1 gene therapy improves glucose homeostasis in Zucker diabetic fatty rats Journal Of Gene Medicine 10:260~268,2008 림프종 환자에서 양전자단층촬영술상 발견된 비기능성 뇌하수체선종 1예 대한내분비학회지(Journal Of The Korean Society Of Endocrinology) 23 2:137~141,2008 Serum parathyroid hormone is associated with carotid intima-media thickness in postmenopausal women International Journal Of Clinical Practice 62:1352~1357,2008 HoxD10 gene delivery using adenovirus/adeno-associate hybrid virus inhibits the proliferation and tumorigenicity of GH4 pituitary lactotrope tumor cells Biochemical And Biophysical Research Communications 371:371~374,2008 Splice variants of the forkhead box protein AFX exhibit dominant negative activity and inhibit AFX??-mediated tumor cell apoptosis PLoS One 3 7:e2743~,2008 Multiple endocrine neoplasia type 1 with multiple leiomyomas linked to a novel mutation in the MEN1 gene Yonsei Medical Journal 49:655~661,2008 한국 제2형 당뇨병환자에서 죽상동맥경화증 유무의 예측인자로서 허리둘레 기준치 분석 임상당뇨병학회지(Clinical Diabetes) 9 3:219~227,2008 편측무도증으로 발현하여 처음 진단된 제2형 당뇨병 1예 임상당뇨병학회지(Clinical Diabetes) 9 3:213~218,2008 Echogenic carotid artery plaques are associated with vertebral fractures in postmenopausal women with low bone mass Calcified Tissue International 82 6:411~417,2008 Functional expression of CXCR4 in somatotrophs: CXCL12 activates GH gene, GH production and secretion, and cellular proliferation Journal Of Endocrinology 199:191~199,2008 A Phenotypic Spectrum of Sexual Development in Dax1 (Nr0b1)-Deficient Mice: Consequence of the C57BL/6J Strain on Sex Determination Biology Of Reproduction 79 6:1038~1045,2008 갈색세포종에서 18FDG의 전신 갈색지방조직 섭취를 보인 증례 1예 대한내과학회지 75:s858~s861,2008 Thyroglobulin measurement in fine-needle aspirate washouts: the criteria for neck node dissection for patients with thyroid cancer Clinical Endocrinology 70 1:145~151,2009 TUMOR TISSUE IDENTIFICATION IN THE PSEUDOCAPSULE OF PITUITARY ADENOMA: SHOULD THE PSEUDOCAPSULE BE REMOVED FOR TOTAL RESECTION OF PITUITARY ADENOMA? Neurosurgery 64 3:62~70,2009 Role of the Phosphatidylinositol-3-Kinase and Extracellular Regulated Kinase Pathways in the Induction of Hypoxia-Inducible Factor (HIF)-1 Activity and the HIF-1 Target Vascular Endothelial Growth Factor in Ovarian Granulosa Cells in Response to Follicle-Stimulating Hormone Endocrinology 150 2:915~928,2009 Reversal of diabetes in rats Using GLP-1-expressing adult pancreatic duct-like precursor cells transformed from acinar to ductal cells Stem Cells And Development 18 7:991~1002,2009 두 종류의 항체를 보유한 자가면역성 저혈당 1예 임상당뇨병학회지(Clinical Diabetes) 10 2:123~128,2009 Adiponectin Stimulates Osteoblast Differentiation Through Induction of COX2 in Mesenchymal Progenitor Cells Stem Cells 27 9:2254~2262,2009 Insulin-secreting cells from human eyelid-derived stem cells alleviate type I diabetes in immunocompetent mice Stem Cells 27 8:1999~2008,2009 Insulin resistance and carotid atherosclerosis in patients with type 2 diabetes Atherosclerosis 205 1:309~313,2009 Fox12, a forkhead transcription factor, modulates nonclassical activity of the estrogen receptor-α Endocrinology 150 111:5085~5093,2009 Predicting Recurrence of Nonfunctioning Pituitary Adenomas Journal of clinical endocrinology and metabolism 94:4406~4413,2009 Association between low bone mass and aortic valve sclerosis in Koreans Clinical Endocrinology 71 6:792~797,2009 The effect of rosiglitazone on insulin sensitivity and mid-thigh low-density muscle in patients with Type 2 diabetes DIABETIC MEDICINE 27 1:30~36,2010 A dual-reporter system for specific tracing of pancreatic -cell lines that non-invasively measures viable in vivo islet cells BIOTECHNOLOGY LETTERS 32:53~57,2010 Discrimination of prolactinoma from hyperprolactinemic non-functioning adenoma ENDOCRINE 37:140~147,2010 Visceral adiposity and leptin are independently associated with C-reactive protein in Korean type 2 diabetic patients Acta Diabetologica 47 2:113~118,2010 Adiponectin is independently associated with apolipoprotein B to A-1 ratio in Koreans Metabolism-Clinical and Experimental 59 5:677~682,2010 Protective effects of magnesium lithospermate B against diabetic atherosclerosis via Nrf2-ARE-NQO1 transcriptional pathway Atherosclerosis 211 1:69~76,2010 Natural therapeutic magnesium lithospermate B potently protects the endothelium from hyperglycaemia-induced dysfunction Cardiovascular Research 87:713~722,2010 Relationship Between Visceral Adiposity and Bone Mineral Density in Korean Adults Calcified Tissue International 87 3:218~225,2010 The effect of mosapride (5HT-4 receptor agonist) on insulin sensitivity and GLUT4 translocation DIABETES RESEARCH AND CLINICAL PRACTICE 87 3:329~334,2010 A case of fugitive acromegaly, initially presented as invasive prolactinoma ENDOCRINE 38 1:1~5,2010 Absence of activating mutations of CXCR4 in pituitary tumours Clinical Endocrinology 72 2:209~213,2010 Role of ultrasonography in outcome prediction in subclinical hypothyroid patients treated with levothyroxine Endocrine Journal 57 1:15~22,2010 Effect of beta 4 Integrin Knockdown by RNA Interference in Anaplastic Thyroid Carcinoma Anticancer Research 30 11:4485~4492,2010 Triiodothyronine level predicts visceral obesity and atherosclerosis in euthyroid, overweight and obese subjects: T3 and visceral obesity OBESITY RESEARCH & CLINICAL PRACTICE 4:e315~e323,2010 The cyclic pentapeptide d-arg3FC131, a CXCR4 antagonist, induces apoptosis of somatotrope tumor and inhibits tumor growth in nude mice ENDOCRINOLOGY 152 2:536~544,2011 Metabolic Parameters and Nonalcoholic Fatty Liver Disease in Hypopituitary Men HORMONE AND METABOLIC RESEARCH 43 1:48~54,2011 Effect of Zoledronic Acid on Acro-Osteolysis and Osteoporosis in a Patient with Hajdu-Cheney Syndrome YONSEI MEDICAL JOURNAL 52 3:543~546,2011 Clinical management and outcome of 36 invasive prolactinomas treated with dopamine agonist JOURNAL OF NEURO-ONCOLOGY 104 1:195~204,2011 SUSTAINED-RELEASE RECOMBINANT HUMAN GROWTH HORMONE IMPROVES BODY 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ENDOCRINOLOGY 152 2:536~544,2011 Inhibition of Akt/FOXO3a signaling by constitutively active FOXO3a suppresses growth of follicular thyroid cancer cell lines. CANCER LETTERS 314 1:34~40,2012 Resveratrol prevents streptozotocin-induced diabetes by inhibiting the apoptosis of pancreatic β-cell and the cleavage of poly (ADP-ribose) polymerase ENDOCRINE JOURNAL 59 2:103~109,2012 Nonmuscle Myosin Heavy Chain and Histone H3 are Intracellular Binding Partners of Lithospermic Acid B and Mediate its Antiproliferative Effect on VSMCs. 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NEUROSURGERY 70(2 Suppl Operative):250~256,2012 Anti-inflammatory effect of quercetin in a whole orbital tissue culture of Graves' orbitopathy BRITISH JOURNAL OF OPHTHALMOLOGY 96 8:1117~1121,2012 Antifibrotic Effects of Quercetin in Primary Orbital Fibroblasts and Orbital Fat Tissue Cultures of Graves’ Orbitopathy INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 53 9:5921~5929,2012 Clinical features of thyroid-associated ophthalmopathy in clinically euthyroid Korean patients. EYE 26 9:1263~1269,2012 Spontaneous Non-Traumatic Stress Fractures in Bilateral Femoral Shafts in a Patient Treated with Bisphosphonates The Korean Journal of Internal Medicine 27 1:98~102,2012 Effect of teriparatide on pregnancy and lactation-associated osteoporosis with multiple vertebral fractures JOURNAL OF BONE AND MINERAL METABOLISM 30 5:596~601,2012 Protocatechuic aldehyde inhibits migration and proliferation of vascular smooth muscle cells and intravascular thrombosis. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 423 1:116~121,2012 Surgical and Endocrinological Outcomes in the Treatment of Growth Hormone-Secreting Pituitary Adenomas with a Shift in the Surgical Paradigm NEUROSURGERY 71 2 Suppl Operative:ons192~ons203,2012 성장호르몬 분비 뇌하수체 종양의 수술적 완치 후 발견된 지연형 자가면역 당뇨병 1예 대한내분비학회지 27 4:318~322,2012 A 47,X,+t(X;X)(p22.3;p22.3)del(X)(p11.23q11.2),Y Klinefelter Variant with Morbid Obesity YONSEI MEDICAL JOURNAL 54 2:538~540,2013 Therapeutic Effects of Water Soluble Danshen Extracts on Atheroxclerosis EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE 2013:623639-1~623639-11,2013 Cigarette smoke extract-induced adipogenesis in Graves’ orbital fibroblasts is inhibited by quercetin via reduction in oxidative stress JOURNAL OF ENDOCRINOLOGY 216 2:145~156,2013 Treatment of upper eyelid retraction related to thyroid-associated ophthalmopathy using subconjunctival triamcinolone injections GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY 251 1:261~270,2013 Analysis of [18F] fluoro-2-deoxy-D-glucose positron emission tomography findings in patients with pituitary lesions The Korean Journal of Internal Medicine 28 1:81~88,2013 Cigarette-Smoke-Extract-Induced Adipogenesis in Graves' Orbital Fibroblasts Is Inhibited by Quercetin JOURNAL OF ENDOCRINOLOGY 216 2:145~156,2013 Quantitative Structure-Activity Relationship Study of Aromatic Inhibitors against Rat Lens Aldose - Reductase Activity using Variable Selections MEDICINAL CHEMISTRY 9 3:410~419,2013 Nationwide survey of acromegaly in South Korea CLINICAL ENDOCRINOLOGY 78 4:577~585,2013 |